Pegcetacoplan offered better haemtologic and clinical outcomes than eculizumab in a UK trial of patients with paroxysmal nocturnal haemoglobinuria (PNH). The therapy, which targets complement C3 could offer an option to patients who experience persistent anaemia despite long-term therapy with C5 inhibitors. PNH is a rare acquired disease, characterised by complement-mediated haemolysis. Patients often suffer ...
Paroxysmal nocturnal haemoglobinuria: targeting C3 delivers better outcomes
By Dave Levitan
22 Mar 2021