The presence or absence of two microdeletions combined with minimal residual disease (MRD) and National Cancer Institute (NCI) risk can improve early stratification of children with acute lymphoblastic leukaemia (ALL). The Australian-led research involving 475 children with non-high risk precursor B-cell ALL enrolled in the ANZCHOG study ALL8 found IKZF1 and P2RY8-CRLF2 deletions were predictive of relapses. ...
New model of risk stratification for ALL in kids
By Mardi Chapman
6 Dec 2017