DOAC reversal agent reduces anti-factor Xa activity

The DOAC reversal agent andexanet has been shown to rapidly and markedly reduce anti-factor Xa activity in patients with acute major bleeding associated with the use of a factor Xa inhibitor. The final results of the ANNEXA-4 study,¬†published in NEJM, also showed that “82% of patients had excellent or good haemostatic efficacy at 12 hours.” ...

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