Blood cancers

BRCA2 gene mutations found in childhood lymphoma

Evidence is strengthening for an association between germline BRCA2 mutations and paediatric or adolescent non-Hodgkin lymphoma. A research letter in JAMA Oncology described the findings of whole genome sequencing in almost 800 five-year survivors of Hodgkin and non-Hodgkin lymphoma. The study found pathogenic or likely pathogenic BRCA2 mutations in 13 survivors of Hodgkin lymphoma and ...

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