Surgery can be effective in a highly selected group of patients with true PPI-refractory, reflux-related heartburn, research shows. A US randomised controlled trial compared laparoscopic Nissen fundoplication versus omeprazole plus baclofen and desipramine if required (active medical treatment) or omeprazole plus placebo (control medical treatment). The 78 participants were mostly white, male veterans referred for ...
Refractory heartburn: patient selection important before surgery
By Mardi Chapman
24 Oct 2019