gastroenterology
Coeliac disease

No-biopsy approach supported for diagnosis of coeliac disease in adults

The serology-based ‘no-biopsy’ approach recommended for diagnosis of paediatric coeliac disease can also be used in adults, an international study suggests. Instead of relying on upper GI endoscopy to identify duodenal mucosal abnormalities, the diagnosis of CD can be confirmed by a 10-fold increase in serum IgA antitissue transglutaminase (tTG) antibody levels, according to research published ...

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