gastroenterology
Medicines

New guidelines on medical management of opioid-induced constipation

New guidelines for the treatment of opioid-induced constipation recommend peripherally-acting mu-opioid receptor antagonist (PAMORA) drugs, such as naloxegol (Movantik) in patients who do not respond to laxatives. The clinical guidelines released by the American Gastroenterology Association, make evidence-based recommendations based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. Developed in response to the growing use of ...

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