gastroenterology
Infections

New antibiotics needed for C. difficile as promising drug abandoned

A final line has been drawn under cadazolid as an initially promising but ultimately disappointing treatment for the management of C. difficile infections. The IMPACT 1 and 2 trials of the novel quinoxolidinone antibiotic versus vancomycin, published together in The Lancet Infectious Diseases, failed to show overall superiority of cadazolid over vancomycin. “Further commercial development ...

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