More effort needed to reduce methotrexate overdosing

Manufacturers, the TGA and health professionals need to do more to reduce the risk of potentially fatal overdosing with methotrexate, most commonly from taking the drug daily rather than weekly, an Australian study has concluded. Dr Rose Cairns, from the NSW Poisons Information Centre, and colleagues identified 22 methotrexate-associated deaths in coroners’ cases nationwide between ...

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