Early thiopurine use avoids need for surgery in UC

Early thiopurine maintenance therapy – within the first five years of an ulcerative colitis diagnosis and maintained for at least six months – is associated with a 9-fold relative risk reduction in colectomy (HR 0.10) and 4-fold risk reduction in disease extent progression (HR 0.26). A study of 982 patients from the Sydney IBD Cohort ...

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