Denosumab (Xgeva) should not be prescribed to patients with unhealed lesions from dental or oral surgery, the TGA has confirmed in its latest Medicines Safety Update. Osteonecrosis of the jaw (ONJ) is already a known adverse event highlighted in the PI documents of both brands marketed in Australia – Prolia and Xgeva. However the TGA ...
Xgeva contraindicated for patients with dental complications
21 Apr 2016