Dr Sandra Galic: targeting AMPK-ACC regulation to prevent rebound weight gain

Dr Sandra Galic is aiming to identify the molecular mechanisms of energy balance regulation. She is a senior research officer in the Protein Chemistry and Metabolism Unit at St VincentÂ’s Institute of Medical Research.

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Challenge: can you describe the aim of this project in 10 words? How does increased energy demand signal the need for compensatory energy intake? What were some of your key findings? The focus of this study was the enzyme AMP-activated protein kinase (AMPK), which is a well-known regulator of cellular energy metabolism. We found that ...

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