endocrinology
Type 1 diabetes

Gut microbiome provides clues to T1D pathogenesis

Australian children with islet autoimmunity who progress to types 1 diabetes have been shown to have gut microbiome dysbiosis, increased small intestinal permeability and reduced circulating short-chain fatty acid (SCFA) levels. The same changes were not apparent in children with islet autoimmunity who did not progress to type 1 diabetes, according to Professor Jenny Couper ...

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