endocrinology
Hormones

Aldosteronism is the key to resistant hypertension: spironolactone study

Primary or secondary aldosteronism has been confirmed as a major underlying cause of resistant hypertension, following success in treating the condition with the mineralocorticoid receptor antagonist spironolactone. A follow up of 269 patients with resistant hypertension participating in a trial of spironolactone found further evidence pointing to the hypertension being a salt-retaining state due to ...

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