Autoimmune diseases

Two trials compare treatments for pemphigus vulgaris

Rituximab is superior to mycophenolate mofetil in the management of patients with moderate to severe pemphigus vulgaris, a new study shows. A phase 3 international trial, published in the NEJM, randomised 135 patients to either IV rituximab or oral mycophenolate, in addition to oral prednisone tapered to discontinuation by 24 weeks. The US-led study found ...

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