Celecoxib loses some of its safety advantages over non-selective NSAIDs when taken concomitantly with aspirin, a retrospective analysis of almost 24,000 patients with arthritis shows. When used without aspirin, a low daily dose (200mg) of the COX-2 selective inhibitor had a more favourable overall safety profile than ibuprofen and naproxen, a review of on-treatment data ...
How does concomitant aspirin use modify NSAID cardiovascular safety?
By Michael Woodhead
27 Apr 2018