Caution on off-label DOAC use in LV thrombus

A cautionary note has been sounded on off-label use of DOACs in patients with left ventricular thrombi, with researchers warning it is associated with a higher risk of stroke or systemic embolism than warfarin. A US study, published in JAMA Cardiology, suggests extrapolating from DOAC use in approved indications such as non-valvular AF is problematic.  ...

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