Umbrella review clears fogginess about uric acid


There is no evidence to expand the use of uric acid lowering drugs beyond current indications for gout or nephrolithiasis, according to a comprehensive review of the evidence. The ‘umbrella review’ comprised 144 meta-analyses of observational studies, 32 meta-analyses of randomised controlled trials and 107 Mendelian randomisation analyses. The findings should put to bed any ...


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