At today’s opening plenary here in Darwin ‘Rheumatology in a nutshell’ Dr Dan Kastner, head of inflammatory diseases at Princeton University, gave delegates his top 10 advances in autoinflammatory diseases over the last year.
Dan’s top 10*
- Discovery of a new pyrin-associated disease cracks the autoinflammatory riddle of the sphinx.
- The proteasome strikes back: new mutations and CANDLE
- Adult onset autoinflammatory disease caused by lineage somatic mutations
- MHC Class II caught with systemic JIA
- TNFAIP3/A20 finds new ways to misbehave
- NLRC4 plus FCAS
- The expanding spectrum of ADA2
- Pneumovax and flares of CAPS
- Vibratory uritcaria makes its appearance on the autoinflammatory stage
- Share consortium recommendations for the management of autoinflammatory diseases.
*The links go to the papers Dr Kastner referred to in his talk.